По-високата инсулинова чувствителност се асоциира в по-висока продължителност на живота при мишките.
"Our findings put a mechanism behind what your mother told when you were growing up--eat a good diet and exercise, and it will keep you healthy," said White. "Diet, exercise and lower weight keep your peripheral tissues sensitive to insulin. That reduces the amount and duration of insulin secretion needed to keep your glucose under control when you eat. Therefore, the brain is exposed to less insulin. Since insulin turns on Irs2 in the brain, that means lower Irs2 activity, which we've linked to longer lifespan in the mouse."
източник: http://www.soulcysters.net/article-new- ... ed-215764/
"The easiest way to keep insulin levels low in the brain," White says, "is old-fashioned diet and exercise." Although obesity and sedentary lifestyles tune down the body's sensitivity to insulin, exercise can bring it back and reduce blood insulin levels. Eating smaller meals keeps insulin low in the bloodstream, ensuring that less reaches the brain. The new drugs designed to fight insulin resistance and type 2 diabetes might have a similar effect.
"This study provides a new explanation of why it's good to exercise and not eat too much," says White. "It has less to do with how we look, and more to do with a healthy brain, especially in old age."
The study also calls into question the long-term effects of insulin therapy for diabetes, White adds. "High insulin should be the short term solution to insulin resistance, because it might damage the brain in the long run," he says. Better treatments for diabetes and healthy aging, he suggests, should concentrate on sensitizing the body's cells to low amounts of insulin.
източник: http://www.hms.harvard.edu/news/pressre ... aling.html
т.е. в нашия контекст:
- яко НВД за подобрена инсулинова сенситивност
- яко НВД за ниски нива на инсулин
- яко щанги и спорт като цяло за ниски нива на инсулин
Ниски нива на инсулин - по-здрав мозък и по-дълъг живот. По-малко рак. По-бавно стареене.
яко
